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polymerase chain reaction
noun
: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
—abbreviation PCR
Examples of polymerase chain reaction in a Sentence
Recent Examples on the Web
Your healthcare provider can test your blood for antibodies to the virus using a polymerase chain reaction (PCR) blood test.4
Treatments for Varicella-Zoster Virus
The goal of varicella-zoster treatment is to improve the symptoms and shorten the time of illness.
—Carrie Madormo, Rn, Health, 3 Nov. 2024
But in 1984, the American biochemist Kary Mullis invented polymerase chain reaction (PCR), a method of amplifying very small amounts of DNA so it can be studied in detail.
—David Cox, WIRED, 2 Dec. 2020
Our primary method of testing has been through polymerase chain reaction [PCR], which provides results in eight to 10 hours.
—Paul Adepoju, Scientific American, 8 Oct. 2024
To help contain the spread, doctors and public health officials prioritized polymerase chain reaction (PCR) testing.
—Robert Pearl, Forbes, 30 Sep. 2024
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Word History
First Known Use
1985, in the meaning defined above
Time Traveler
The first known use of polymerase chain reaction was
in 1985
Dictionary Entries Near polymerase chain reaction
Cite this Entry
“Polymerase chain reaction.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polymerase%20chain%20reaction. Accessed 21 Nov. 2024.
Medical Definition
polymerase chain reaction
noun
: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, binding a primer to each single strand at the end of the given DNA segment where synthesis will start, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
—abbreviation PCR
More from Merriam-Webster on polymerase chain reaction
Britannica.com: Encyclopedia article about polymerase chain reaction
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